LACTOFERRINE – www.lactoferrine.es

LACTOFERRINE

Lactoferrine is a natural support for the immune defenses, manufactured from milk protein, antibiotic free, BSE free, pasture fed, out door herds, supplied direct from our company to Industries, Manufacturing Companies, Industrialists, Distributors, Agentes and other economic operators.

From time ago there is a mounting and increasing research supporting the health benefits of Lactoferrine.This research indicates that Lactoferrine has natural immune defense supporting characteristics. It can be taken by any age group and well tolerated.

Dietary Supplement.

Lactoferrine has previously been shown to be beneficial for supporting the normal balance of micro-organisms in the intestine. This is particularly useful following a course of antibiotics. For more information about the History, Research, Composition and the health Benefits of Lactoferrine, please contact us

Lactoferrine plays also several biological roles related to its iron binding ability, immune support and antioxidant activities, and its ability to bind iron. Lactoferrine binds the free iron thus far reducing the amount of oxidative free radicals

Lactoferrine is also acting in support of intestinal health by scavenging iron and supporting the balance of healthy flora in the G.I. tract. By modulating healthy levels of iron in the body, Lactoferrine plays a key role in maintaining general good health.

What is Lactoferrine?

Lactoferrine is a glycoprotein that belongs to the iron transporter or transferrin family. It was originally isolated from bovine milk, where it is found as a minor protein component of whey proteins. Lactoferrine contains 703 amino acids and has a molecular weight of 80 kilodaltons. In addition to its presence in milk, it is also found in exocrine secretions of mammals.

Lactoferrine is considered a multifunctional or multi-tasking protein. It appears to play several biological roles. Owing to its iron-binding properties, lactoferrine is thought to play a role in iron uptake by the intestinal mucosa of the suckling neonate. That is, it appears to be the source of iron for breast-fed infants.

Three isoforms of lactoferrine have been isolated: lactoferrin-alpha, lactoferrin-beta and lactoferrin-gamma. Lactoferrin-beta and lactoferrin-gamma have RNase activity, whereas lactoferrin-alpha does not. Receptors for lactoferrine are found in monocytes, lymphocytes, neutrophils, intestinal tissue and on certain bacteria. Lactoferrine is abbreviated LF and Lf. Bovine lactoferrin is abbreviated bLF.

Bovine lactoferrin, derived from whey proteins, is marketed as a nutritional supplement. Supplemental lactoferrin typically contains low amounts of iron.

How it works

Little is known of the pharmacokinetics of oral lactoferrine. Lactoferrine appears much more resistant to proteolytic action than most dietary proteins. Lactoferrine is digested in the intestine to the bioactive peptide lactoferricine. Most of the possible actions of oral lactoferrine may be confined to the gut. There is some preliminary evidence that lactoferrine and lactoferricine may be absorbed, in part, from the lumen of the small intestine into enterocytes and that these molecules enter other cells as well. However, this remains unclear.